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Olumacostat glasaretil
CAS No. 1261491-89-7
Olumacostat glasaretil ( Olumacostat glasaretil; DRM01B; DRM-01B )
Catalog No. M11083 CAS No. 1261491-89-7
A small molecule inhibitor of acetyl coenzyme A (CoA) carboxylase (ACC); inhibits de novo lipid synthesis in primary and transformed human sebocytes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 55 | In Stock |
|
| 5MG | 87 | In Stock |
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| 10MG | 132 | In Stock |
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| 25MG | 251 | In Stock |
|
| 50MG | 430 | In Stock |
|
| 100MG | 627 | In Stock |
|
| 200MG | 893 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameOlumacostat glasaretil
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NoteResearch use only, not for human use.
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Brief DescriptionA small molecule inhibitor of acetyl coenzyme A (CoA) carboxylase (ACC); inhibits de novo lipid synthesis in primary and transformed human sebocytes.
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DescriptionA small molecule inhibitor of acetyl coenzyme A (CoA) carboxylase (ACC); inhibits de novo lipid synthesis in primary and transformed human sebocytes; reduces saturated and monounsaturated fatty acyl chains across lipid species, including di- and triacylglycerols, phospholipids, cholesteryl esters, and wax esters; significantly reduces hamster ear sebaceous gland size; a pro-drug of TOFA with enhance delivery in vivo.Other Indication Phase 3 Clinical
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SynonymsOlumacostat glasaretil; DRM01B; DRM-01B
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaOther Indications
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IndicationOther Disease
Chemical Information
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CAS Number1261491-89-7
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Formula Weight481.62
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Molecular FormulaC26H43NO7
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(C1=CC=C(OCCCCCCCCCCCCCC)O1)OCC(N(CC(OCC)=O)C)=O
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Chemical Name2-Furancarboxylic acid, 5-(tetradecyloxy)-, 2-[(2-ethoxy-2-oxoethyl)methylamino]-2-oxoethyl ester
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bissonnette R, et al. J Am Acad Dermatol. 2017 Jan;76(1):33-39.
2. Hunt DW, et al. J Invest Dermatol. 2017 Jul;137(7):1415-1423.
3. Melnik BC. J Invest Dermatol. 2017 Jul;137(7):1405-1408.
2. Hunt DW, et al. J Invest Dermatol. 2017 Jul;137(7):1415-1423.
3. Melnik BC. J Invest Dermatol. 2017 Jul;137(7):1405-1408.
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